The world's urban poor and the illiterate are going to be increasingly disadvantaged and are in danger of being left behind. The web has added a new dimension to the gap between the first world and the developing world. We have to start talking about a human right to connect.
One way to think about the magnitude of the changes to come is to think about how you went about your business before powerful Web search engines. You probably wouldn't have imagined that a world of answers would be available to you in under a second. The next set of advances will have an different effect, but similar in magnitude.