Towards the end of the military service, I had to make what I assume has been the most important decision in my career: to start a residency in clinical medicine, in surgery, which was my favorite choice, or to enroll into graduate school and start a career in scientific research. It was clear to me that I was heading for graduate school.
The problem of different sensitivities of distinct protein groups to lysosomal inhibitors has remained unsolved and may have served as an important trigger in the future quest for a non-lysosomal proteolytic system that may be involved in at least certain aspects of intracellular protein degradation.
The development of methods to monitor protein dynamics in cells together with the discovery of specific and general lysosomal inhibitors have resulted in the identification of different classes of cellular proteins, long- and short-lived, and the findings of the differential effects of the inhibitors on these groups.
We are a country that lacks riches. The Jewish brain, that's what we have. Everything that we've had and will have in this country is the direct and clear product of higher education. If we harm this system, we will drastically decline and cease to exist.
The scale of time for a politician runs between one primary and the next, and in Israel, this means two to three years because elections almost never take place once every four years as stipulated by law. The timetable for a system of research is completely different.